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  • 產品名稱: Recombinant Human OLR1 protein
  • 產品貨號: CSP00848
  • 貨期: 現(xiàn)貨
  • 價格與訂購: 1800
  • 數(shù)量:
    庫存: 100
  • 規(guī)格: 50μg 100μg 1mg
  • 產品信息
  • 如何訂購
    概述(Summary)
    英文全稱
    Recombinant Human OLR1 protein
    純度(Purity)
    >90% as determined by SDS-PAGE
    內毒素(Endotoxin level)
    Please contact with the lab for this information.
    蛋白構建(Construction)
    A DNA sequence encoding the human OLR1 (Leu81-Gln273) was fused with His tag
    Accession #
    P78380
    表達宿主(Host)
    E.coli
    種屬(Species)
    Homo sapiens (Human)
    預測分子量(Predicted Molecular Mass)
    23.19 kDa
    制劑(Formulation)
    Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
    運輸方式(Shipping)
    In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
    穩(wěn)定性&儲存(Stability &Storage)
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    復溶(Reconstitution)
    Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
    背景(Background)
    背景介紹
    Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1 or OLR1), also known as lectin-type oxidized LDL receptor 1 (LOX1), is a receptor protein that belongs to the C-type lectin superfamily. LOX1 is a multi-ligand receptor originally identified as the endothelial oxidized LDL receptor. OLR1 / LOX1 was isolated from an aortic endothelial cell, and recently it has been discovered in macrophages and vascular smooth muscle cells in artery vessels. The expression of LOX1 is inducted by inflammatory stimuli and oxidative stimuli. This protein binds, internalizes and degrades oxidized low-density lipoprotein. LOX1 may play an important role in the progression of vulnerable carotid plaque and might regulate vulnerable plaque formation in cooperation with MMPs and TIMP-2. In clinical, LOX1 is thought to be involved in the development of atherosclerotic lesions.
    分子別名(Alternative Names)
    Oxidized low-density lipoprotein receptor 1,Ox-LDL receptor 1,C-type lectin domain family 8 member A,Lectin-like oxidized LDL receptor 1,LOX-1,Lectin-like oxLDL receptor 1,hLOX-1,Lectin-type oxidized LDL receptor 1.
    Note
    For research use only .
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