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  • 產(chǎn)品名稱: Recombinant Human IL27 protein
  • 產(chǎn)品貨號(hào): CSP00305
  • 貨期: 現(xiàn)貨
  • 價(jià)格與訂購(gòu): 1800
  • 數(shù)量:
    庫(kù)存: 100
  • 規(guī)格: 50μg 100μg 1mg
  • 產(chǎn)品信息
  • 如何訂購(gòu)
    概述(Summary)
    英文全稱
    Recombinant Human IL27 protein
    純度(Purity)
    >90% as determined by SDS-PAGE
    內(nèi)毒素(Endotoxin level)
    Please contact with the lab for this information.
    蛋白構(gòu)建(Construction)
    A DNA sequence encoding the human IL27 (Phe29-Pro243) was fused with His tag
    Accession #
    Q8NEV9
    表達(dá)宿主(Host)
    E.coli
    種屬(Species)
    Homo sapiens (Human)
    預(yù)測(cè)分子量(Predicted Molecular Mass)
    26.67 kDa
    制劑(Formulation)
    Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
    運(yùn)輸方式(Shipping)
    In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
    穩(wěn)定性&儲(chǔ)存(Stability &Storage)
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    復(fù)溶(Reconstitution)
    Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
    背景(Background)
    背景介紹
    IL-27 protein is a member of the IL-6 superfamily, which is expressed on monocytes, endothelial cells and dendritic cells. IL-27 protein is also referred as the IL-12 p35-related protein, p28, is one subunit of a heterodimeric cytokine complex, and associates with another subunit EBI3 (EBV-induced gene 3), an IL-12 p4-related protein (IL-27B). IL-27 protein is an early product of activated antigen-presenting cells and drives rapid clonal expansion of naive CD4(+) T cells and plays a role in the early regulation of Th1 cells initiation which drives efficient adaptive immune response. IL-27 protein has an antiproliferative activity on melanomas through WSX-1/STAT1 signaling. Thus, IL-27 protein may be an attractive candidate as an antitumor agent applicable to cancer immunotherapy.
    分子別名(Alternative Names)
    Interleukin-27 subunit alpha,IL-27 subunit alpha,IL-27-A,IL27-A,Interleukin-30,p28.
    Note
    For research use only .
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