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    • 產(chǎn)品名稱: Anti SARS-CoV-2(2019-nCoV) NSP3 polyclonal antibody
    • 產(chǎn)品貨號: CSP235
    • 貨期: 現(xiàn)貨
    • 價格與訂購: 2880
    • 數(shù)量:
      庫存: 100
    • 規(guī)格:
    • 產(chǎn)品信息
    • 如何訂購
      產(chǎn)品名(Product Name)
      Anti SARS-CoV-2(2019-nCoV) NSP3 polyclonal antibody
      貨號(Catalog No.)
      CSP235
      描述(description)
      Produced in rabbits immunized with purified,Recombinant SARS-CoV-2 NSP3 protein
      特異性(Spcificty)
      Recognizes SARS-CoV-2 NSP3 protein
      亞型(Isotype)
      IgG
      克隆性(Clonality)
      Polyclonal
      別名(Alternative names)
      Non-structural protein 3,PL2-PRO,Papain-like proteinase,PL-PRO,Replicase polyprotein 1a
      偶連物(Conjugation)
      Unconjugate
      種屬反應(yīng)性(Species reactivity)
      Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2)
      應(yīng)用實驗(Tested applications)
      Elisa
      免疫原(Immunogen)
      Recombinant SARS-CoV-2 NSP3(Glu1024-Gln1198)
      icon
      背景(Background)
      Responsible for the cleavages located at the N-terminus of the replicase polyprotein. In addition, PL-PRO possesses a deubiquitinating/deISGylating activity and processes both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains from cellular substrates. Participates together with nsp4 in the assembly of virally-induced cytoplasmic double-membrane vesicles necessary for viral replication. Antagonizes innate immune induction of type I interferon by blocking the phosphorylation, dimerization and subsequent nuclear translocation of host IRF3. Prevents also host NF-kappa-B signaling.
      狀態(tài)(Form)
      Liquid
      穩(wěn)定性&儲存(Stability &Storage)
      Use a manual defrost freezer and avoid repeated freeze thaw cycles.
      Store at 2 to 8 °C for one week .
      Store at -20 to -80 °C for twelve months from the date of receipt.
      儲存溶液(Buffer)
      PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
      應(yīng)用實驗及稀釋比例(Dilution Range)
      Elisa:1:4000~1:8000
      濃度(Concentration)
      0.33mg/ml
      icon
      分子量(MW)
      200kDa
      Accession #
      P0DTC1
      宿主(Host)
      Rabbit
      Note
      For research use only .
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