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Rabbit Polyclonal Antibody 

IgG

Antigen Affinity Purification 

WB, IP, ELISA

Succinylated Protein 

Succinylated BSA

PBS with 0.1% sodium azide and 50% glycerol, pH 7.2 

Store at -20℃. Do not aliquot 

WB: 1:1000-2000  IP: 1:5000-10000 

Succinylation   is a posttranslational modification where a succinyl group (-CO-CH2-CH2-CO2H)   is added to a lysine residue of a protein molecule. This modification is   found in many proteins, including histones. The potential role of   succinylation is under investigation, but as addition of succinyl group   changes lysine's charge from +1 to ?1 (at physiological pH) and introduces a   relatively large structural moiety (100 Da), bigger than acetylation (42 Da)   or methylation (14 Da), it is expected to lead to more significant changes in   protein structure and function. By analogy to acetylation, it has been   suggested that succinyl-CoA is the cofactor of enzyme-mediated lysine   succinylation.

For research use only .