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  • 159-2642-3062 027-65317797
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    • 產(chǎn)品名稱: Recombinant Human UBC9 protein
    • 產(chǎn)品貨號: CSP00491
    • 貨期: 現(xiàn)貨
    • 價格與訂購: 1800
    • 數(shù)量:
      庫存: 100
    • 規(guī)格: 50μg 100μg 1mg
    • 產(chǎn)品信息
    • 如何訂購
      概述(Summary)
      英文全稱
      Recombinant Human UBC9 protein
      純度(Purity)
      >90% as determined by SDS-PAGE
      內(nèi)毒素(Endotoxin level)
      Please contact with the lab for this information.
      蛋白構(gòu)建(Construction)
      A DNA sequence encoding the human UBC9 (Asp33-Ser158) was fused with His tag
      Accession #
      P63279
      表達宿主(Host)
      E.coli
      種屬(Species)
      Homo sapiens (Human)
      預測分子量(Predicted Molecular Mass)
      15.67 kDa
      制劑(Formulation)
      Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
      運輸方式(Shipping)
      In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
      穩(wěn)定性&儲存(Stability &Storage)
      Use a manual defrost freezer and avoid repeated freeze thaw cycles.
      Store at 2 to 8 °C for one week .
      Store at -20 to -80 °C for twelve months from the date of receipt.
      復溶(Reconstitution)
      Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
      背景(Background)
      背景介紹
      UBE2I is a member of the ubiquitin-conjugating E2 family whose members perform the second step in the ubiquitination reaction. Initially identified as the main process for protein degradation, ubiquitination is believed nowadays to be crucial for a wider range of cellular processes. The outcome of the ubiquitin-conjugation reaction, and thereby the fate of the substrate, is heavily dependent on the number of ubiquitin molecules attached and how these ubiquitin molecules are inter-connected. To deal with this complexity and to allow adequate ubiquitination in time and space, a highly sophisticated conjugation machinery has been developed. In a sequential manner, ubiquitin becomes activated by an ubiquitin-activating enzyme (E1), which then transfers the ubiquitin to a group of ubiquitin-conjugating enzymes (E2s). Next, ubiquitin-loaded E2s are interacting with ubiquitin protein ligases (E3s) and ubiquitin is conjugated to substrates on recruitment by the E3. These three key enzymes are operating in a hierarchical system, wherein two E1s and 35 E2s have been found and hundreds of E3s have been identified in humans.
      分子別名(Alternative Names)
      SUMO-conjugating enzyme UBC9,RING-type E3 SUMO transferase UBC9,SUMO-protein ligase,Ubiquitin carrier protein 9,Ubiquitin carrier protein I,Ubiquitin-conjugating enzyme E2 I,Ubiquitin-protein ligase I,p18.
      Note
      For research use only .
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