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  • 159-2642-3062 027-65317797
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    • 產(chǎn)品名稱: Recombinant Human CDK6 protein
    • 產(chǎn)品貨號: CSP00460
    • 貨期: 現(xiàn)貨
    • 價格與訂購: 1800
    • 數(shù)量:
      庫存: 100
    • 規(guī)格: 50μg 100μg 1mg
    • 產(chǎn)品信息
    • 如何訂購
      概述(Summary)
      英文全稱
      Recombinant Human CDK6 protein
      純度(Purity)
      >90% as determined by SDS-PAGE
      內(nèi)毒素(Endotoxin level)
      Please contact with the lab for this information.
      蛋白構(gòu)建(Construction)
      A DNA sequence encoding the human CDK6 (Met1-Ala326) was fused with His tag
      Accession #
      Q00534
      表達宿主(Host)
      E.coli
      種屬(Species)
      Homo sapiens (Human)
      預(yù)測分子量(Predicted Molecular Mass)
      37.65 kDa
      制劑(Formulation)
      Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
      運輸方式(Shipping)
      In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
      穩(wěn)定性&儲存(Stability &Storage)
      Use a manual defrost freezer and avoid repeated freeze thaw cycles.
      Store at 2 to 8 °C for one week .
      Store at -20 to -80 °C for twelve months from the date of receipt.
      復(fù)溶(Reconstitution)
      Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
      背景(Background)
      背景介紹
      Serine/threonine-protein kinase involved in the control of the cell cycle and differentiation; promotes G1/S transition. Phosphorylates pRB/RB1 and NPM1. Interacts with D-type G1 cyclins during interphase at G1 to form a pRB/RB1 kinase and controls the entrance into the cell cycle. Involved in initiation and maintenance of cell cycle exit during cell differentiation; prevents cell proliferation and regulates negatively cell differentiation, but is required for the proliferation of specific cell types (e.g. erythroid and hematopoietic cells). Essential for cell proliferation within the dentate gyrus of the hippocampus and the subventricular zone of the lateral ventricles. Required during thymocyte development. Promotes the production of newborn neurons, probably by modulating G1 length. Promotes, at least in astrocytes, changes in patterns of gene expression, changes in the actin cytoskeleton including loss of stress fibers, and enhanced motility during cell differentiation. Prevents myeloid differentiation by interfering with RUNX1 and reducing its transcription transactivation activity, but promotes proliferation of normal myeloid progenitors. Delays senescence. Promotes the proliferation of beta-cells in pancreatic islets of Langerhans. May play a role in the centrosome organization during the cell cycle phases.
      分子別名(Alternative Names)
      Cyclin-dependent kinase 6,Cell division protein kinase 6,Serine/threonine-protein kinase PLSTIRE.
      Note
      For research use only .
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