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  • 159-2642-3062 027-65317797
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    • 產品名稱: Recombinant Human CTLA4 protein
    • 產品貨號: CSP00233
    • 貨期: 現(xiàn)貨
    • 價格與訂購: 1800
    • 數量:
      庫存: 100
    • 規(guī)格: 50μg 100μg 1mg
    • 產品信息
    • 如何訂購
      概述(Summary)
      英文全稱
      Recombinant Human CTLA4 protein
      純度(Purity)
      >90% as determined by SDS-PAGE
      內毒素(Endotoxin level)
      Please contact with the lab for this information.
      蛋白構建(Construction)
      A DNA sequence encoding the human CTLA4 (Ala37-Asp161) was fused with His tag
      Accession #
      P16410
      表達宿主(Host)
      E.coli
      種屬(Species)
      Homo sapiens (Human)
      預測分子量(Predicted Molecular Mass)
      14.76 kDa
      制劑(Formulation)
      Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
      運輸方式(Shipping)
      In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
      穩(wěn)定性&儲存(Stability &Storage)
      Use a manual defrost freezer and avoid repeated freeze thaw cycles.
      Store at 2 to 8 °C for one week .
      Store at -20 to -80 °C for twelve months from the date of receipt.
      復溶(Reconstitution)
      Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
      背景(Background)
      背景介紹
      Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands or counterreceptors for these two proteins are the B7 family members, CD8 (B7-1) and CD86 (B7-2). CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may play an important role in their functions. CD152 or cytotoxic T lymphocyte antigen-4 (CTLA-4) is an essential receptor involved in the negative regulation of T cell activation. Because of its profound inhibitory role, CD152 has been considered a sound susceptible candidate in autoimmunity and a persuasive target for cancer immunotherapy. In particular, recent evidence suggests that CD152 is also important in the homeostasis and function of a population of suppressive cells, termed regulatory T cells (Treg).
      分子別名(Alternative Names)
      Cytotoxic T-lymphocyte protein 4,Cytotoxic T-lymphocyte-associated antigen 4,CTLA-4,CD152.
      Note
      For research use only .
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