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  • 產(chǎn)品名稱: Recombinant Human NLRP3 protein
  • 產(chǎn)品貨號(hào): CSP00171
  • 貨期: 現(xiàn)貨
  • 價(jià)格與訂購(gòu): 1800
  • 數(shù)量:
    庫(kù)存: 100
  • 規(guī)格: 50μg 100μg 1mg
  • 產(chǎn)品信息
  • 如何訂購(gòu)
    概述(Summary)
    英文全稱
    Recombinant Human NLRP3 protein
    純度(Purity)
    >90% as determined by SDS-PAGE
    內(nèi)毒素(Endotoxin level)
    Please contact with the lab for this information.
    蛋白構(gòu)建(Construction)
    A DNA sequence encoding the human NLRP3 (Met1-Arg157) was fused with His tag
    Accession #
    Q96P20
    表達(dá)宿主(Host)
    E.coli
    種屬(Species)
    Homo sapiens (Human)
    預(yù)測(cè)分子量(Predicted Molecular Mass)
    19.78 kDa
    制劑(Formulation)
    Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
    運(yùn)輸方式(Shipping)
    In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
    穩(wěn)定性&儲(chǔ)存(Stability &Storage)
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    復(fù)溶(Reconstitution)
    Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
    背景(Background)
    背景介紹
    The Nlrp3 inflammasome is a key controller of the proinflammatory cytokine IL-1beta.The Nlrp3 inflammasome triggers interleukin-1 secretion by myeloid cells in response to endogenous and exogenous danger signals.Mutations in the Nlrp3 (CIAS1, cryopyrin) gene are associated with cryopyrin-associated periodic syndrome, autoinflammatory diseases characterized by excessive IL-1 production and neutrophilia in blood and tissues.Missense mutations of the gene encoding NLRP3 are associated with autoinflammatory disorders characterized with excessive production of interleukin-1beta (IL-1beta).
    分子別名(Alternative Names)
    NACHT, LRR and PYD domains-containing protein 3,Angiotensin/vasopressin receptor AII/AVP-like,Caterpiller protein 1.1,CLR1.1,Cold-induced autoinflammatory syndrome 1 protein,Cryopyrin,PYRIN-containing APAF1-like protein 1.
    Note
    For research use only .
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