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  • 159-2642-3062 027-65317797
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    • 產(chǎn)品名稱: Recombinant Human DKK1 protein
    • 產(chǎn)品貨號: CSP00066
    • 貨期: 現(xiàn)貨
    • 價格與訂購: 1800
    • 數(shù)量:
      庫存: 100
    • 規(guī)格: 50μg 100μg 1mg
    • 產(chǎn)品信息
    • 如何訂購
      概述(Summary)
      英文全稱
      Recombinant Human DKK1 protein
      純度(Purity)
      >90% as determined by SDS-PAGE
      內毒素(Endotoxin level)
      Please contact with the lab for this information.
      蛋白構建(Construction)
      A DNA sequence encoding the human DKK1 (Thr32-His266) was fused with His tag
      Accession #
      O94907
      表達宿主(Host)
      E.coli
      種屬(Species)
      Homo sapiens (Human)
      預測分子量(Predicted Molecular Mass)
      26.77 kDa
      制劑(Formulation)
      Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
      運輸方式(Shipping)
      In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
      穩(wěn)定性&儲存(Stability &Storage)
      Use a manual defrost freezer and avoid repeated freeze thaw cycles.
      Store at 2 to 8 °C for one week .
      Store at -20 to -80 °C for twelve months from the date of receipt.
      復溶(Reconstitution)
      Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
      背景(Background)
      背景介紹
      Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 and promote the internalization of LRP5/6. Dickkopf related protein 1 (DKK-1) was initially identified as an inducer of head formation in Xenopus embryos. DKK-1 protein modulates Wnt signaling pathway during embryonic development. Increased levels of DKK-1 are found in the majority of lung cancers, esophageal squamous cell carcinomas, and hormone-resistant breast cancers, while DKK-1 expression is decreased in malignant melanoma and colorectal cancers.
      分子別名(Alternative Names)
      Dickkopf-related protein 1,Dickkopf-1,Dkk-1,hDkk-1,SK.
      Note
      For research use only .
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