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- 產品名稱： Recombinant Human PIVKA-II/Prothrombin protein,C- His Tag
- 產品貨號： CSMP00554HU
- 貨期： 現(xiàn)貨
- 價格與訂購： 2880
- 數(shù)量：
庫存： 100
- 規(guī)格：
- 產品信息
- 如何訂購
產品名稱（Product name）
Recombinant Human PIVKA-II/Prothrombin protein,C- His Tag
貨號（Catalog#）
CSMP00554HU
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描述（description）
A DNA sequence encoding the human F2（Met1-Glu622）with C-terminal His Tag
表達系統(tǒng)（Expression system）
Mammalian cells
iconiconicon 種屬（Species）
Homo sapiens (Human)
Accession #
P00734
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別名（Alternative names)
Coagulation factor II
實際分子量（Actual Molecular Mass）
85kDa
純度（Purity）
>90% by SDS-PAGE
內毒素（Endotoxin level）
Please contact with the lab for this information.
制劑（Formulation）
Supplied as solution form in PBS, pH7.5/ Supplied as lyophilized from PBS, pH7.5
運輸方式（Shipping）
In general, proteins are shipped out with blue ice unless customers require otherwise.
穩(wěn)定性&儲存（Stability &Storage）
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
復溶（Reconstitution）
Please refer to the instraction in the hard copy of COA.icon
應用（Application）
Calibrator or standard in ELISA, WB, IHC and other possible application
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背景（Background）
Protein Induced by Vitamin K Absence or Antagonist-II (PIVKA-II), also known as Des-γ-carboxy-prothrombin (DCP), is an abnormal form of prothrombin. Normally, the prothrombin’s 10 glutamic acid residues (Glu) in the γ-carboxyglutamic acid (Gla) domain at positions 6, 7, 14, 16, 19, 20,25, 26, 29 and 32 are γ-carboxylated to Gla by vitamin-K dependent γ- glutamyl carboxylase in the liver and then secreted into plasma. In patients with hepatocellular carcinoma (HCC), γ-carboxylation of prothrombin is impaired so that PIVKA-II is formed instead of prothrombin. PIVKA-II is considered as is an efficient biomarker specific for HCC
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For research use only .
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