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- 產(chǎn)品名稱： Research Grade Tocilizumab ( 托珠單抗 )
- 產(chǎn)品貨號(hào)： CSD00661
- 貨期： 現(xiàn)貨
- 價(jià)格與訂購： 2480
- 數(shù)量：
庫存： 10
- 規(guī)格： 100μg
- 產(chǎn)品信息
- 如何訂購
貨號(hào)（Catalog No.）
CSD00661
通用名INN
Tocilizumab
純度(Purity)
>95%
濃度( Concentration)
1mg/ml
Formulation
PBS buffer PH7.5
Source
CHO cells
內(nèi)毒素(Endotoxin level)
Please contact with the lab for this information.
產(chǎn)品描述(Description)
Tocilizumab (Anti-Human IL6R, Humanized Antibody) is an anti-human interleukin-6 receptor (IL-6R) neutralizing antibody,prevents binding of IL-6 to the IL-6R,thereby inhibiting both classic and trans-signaling.Tocilizumab (Anti-Human IL6R, Humanized Antibody) can be used for the treatment of rheumatoid arthritis.
別名(Alternative names)
Atlizumab,MRA/R-1569/RHPM-1/RO-4877533
靶點(diǎn);物種(Specificity target name;species)
IL-6R
活性研究（體外/體內(nèi)研究）(Activity in vitro)
Tocilizumab (Anti-Human IL6R, Humanized Antibody) (1-100 ng/mL; 24 hours, 48 hours) inhibits the cell proliferation (growth rate) in a dose-dependent manner, growth rate by HACM is reduced almost completely by 100 ng/mL tocilizumab.
Tocilizumab (Anti-Human IL6R, Humanized Antibody) (0.001-10,000 μg/ml; 2 days) inhibits Ba/F3-gp130-IL-6R cell proliferation stimulated with hIL-6 with an IC50 of 13.5 ng/ml.
Tocilizumab (Anti-Human IL6R, Humanized Antibody) (1 μM; 6 hours) reduces the phosphorylation of STAT3 in vitro consistent with in vivo SAS cells.
Tocilizumab (Anti-Human IL6R, Humanized Antibody) (1-5 μM; 24 hours) significantly reduces VEGF mRNA expression in SAS cells with serum-free medium.
受體鑒定(Receptor identification)
IgG1
CAS
375823-41-9
存儲(chǔ)條件(Storage)
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Note
For research use only .
地 址：
產(chǎn)品銷售：
E - mail ：
郵 編：
Amily
